Items are an integral part of game-play in The Binding of Isaac: Rebirth. They modify Isaac's Attributes, grant or modify Tear Effects, and much more.
There are two different types of items; Active or Passive items. Passive items always have an effect on Isaac, whereas (most) active items only have an effect after a certain amount of rooms when the space bar is pressed.
To learn more about items, look at the items page on the Binding of Isaac: Rebirth Wiki.
IPECAC Community Mod, as of 1.3 adds approximately 120 new items.
For changes to Afterbirth+ items, see Changes.
Activated Collectibles[ | ]
Name | Icon | Charges | Quote | Description |
---|---|---|---|---|
Angel's Box | Single-use | Reward... | Has a 50% chance to spawn 2 items from the angel room pool or 3 soul hearts. The chance for items increases with higher Faith. | |
Blank Book | 4 rooms | Contains more books inside | On use, will randomly perform the effect of any rechargeable book in the game. | |
Camcorder | Unlimited | Mom! Get the camera! | First use: Records Isaac performing an action (Walking around the room, placing bombs, etc). Next Use: When you press play, the actions performed will be Repeated by a Mulligan. The playback will start from where Isaac is currently standing (not where it was recorded). | |
Can of Beans | 2 rooms | Contains many flavours | Activates the effect of random bean items 3-5 times (May activate the same effect more than once). | |
Cool Shades | Unlimited | Stunt kills | Gives damage up for the room if used immediately after killing an enemy. The timeframe for activating it gets shorter for each successful activation in the room. Failed uses reset the boost. | |
Cyber Bum | He wants your energy! | Grants a familiar that follows you around, picking up batteries and collecting excess charges from rooms you clear if your active item is fully charged (or you didn't have one). Spawns pickups after a certain amount of charges. | ||
Demonic Talisman | 1 Room | It craves for souls! | If used in a room with monsters, it will randomly instantly kill one of them, and add one to its "soul count". Using it again in an empty room will consume the talisman, and yield a reward based on how many monsters have been killed by it. The talisman will change colours based on the reward it will give. | |
Devil's Box | Single-use | Temptation | Upon use, has a 50% chance of spawning 2 items from the devil room pool or dealing 3 hearts of damage. The chance for items increases with higher Evil. | |
Death's Sacrifice | Unlimited | Give your life to prevent your death | Upon use, deals 1 red heart of damage, damages all enemies in the room and spawns creep. Whenever an enemy is killed while this is held, all enemies in the room take damage; this damage increases the more times you activate the item and resets each floor. | |
Vegemite | 12 Seconds | Tastes as good as it sounds | Upon use, on the next time the player shoots, spawns a path of brown creep that damages monsters in the direction the shot was fired. | |
Watermelon | 4 Rooms | Ptooie! | Afte use, grants you an immense tears up and a significant range down for approximately 50 tears. After the 50th tear has been fired, your range and tear rate return to normal. Those tears can be used across rooms and are cumulative if you use it multiple times. The effect is only active while holding the Watermelon. |
Passive Collectibles[ | ]
Name | Icon | Quote | Description |
---|---|---|---|
All-in | Raise the stakes | 1.5x Luck Multiplier. +1 Luck. | |
Angry Tears | >:( | Isaac will occasionally fire an "angry tear" that, when it hits an enemy, will fire another tear towards the nearest enemy. | |
Athlete's Foot | It hurts to move! | - 0.25 Speed. Gives you a tears up based on your average velocity in the last 10 seconds, ranging from 0.9x to 0.5x Fire Delay | |
Ballot | Democracy at its finest | When Isaac first enters a boss room, he will get the option to either keep the current boss in, or switch it out for a different one. Does not work on "fixed" boss fights, with the exception of Mom's Heart/It Lives. | |
Blue Streak | Gotta go fast! | The more coins you have, the faster you move. Getting hit will scatter some of your coins on the ground. If not picked up in time, these coins will fade and disappear. | |
Broken Mask | We are one and everyone | Reduces the requirements for transormations by 1 item, and adds a half soul heart. | |
Bumble Bombs | Buzz, buzz, BOOM! | +5 Bombs. Bombs spawn bees and honey creep when they explode and shoot four stingers diagonally when they explode. | |
Bumble! | Bee friend | Grants a familiar that bounces around the room diagonally, periodically spawning honey creep and spawning bees if there are enemies nearby. | |
Burnt Dollar | Less is more | Sets your coins to 0 and spawns pickups proportionally to how many coins you lost. Each time you enter a new floor with 0 coins, you spawn some pickups and gain a permanent flat +0.5 damage. | |
Charity | Donations... | Unjams the donation machine every floor. Using the donation machine increases the angel room chance. Taking damage makes you drop coins, Enemies can pick up coins and become charmed. | |
Chocolate | Speed + Damage up | Speed, Damage, and HP up. | |
Chrometophobia | Scary currency | Increases your Tears fire rate poportionally to how much money you have. Coins left of the ground cause fear on enemies near them. | |
Clockwork | Tick. Tock. | Your tears alternate between gears and springs. Gears deal 1.2x damage, while springs bounce over enemies and obstacles. | |
Coffee Beans | HP + Speed + Shot Speed WAY up! | HP up, Speed up, and a large Shot Speed up. | |
Coffee! | Can't stop, won't stop! | The faster Isaac moves, the more damage he deals. Damage is based on how fast Isaac is moving when he shoots (Not his current speed stat). | |
Companion Cube | Believe me, it's still alive | Gives you a companion cube familiar that can be pushed around. It will also dash towards enemies above and to the sides of it, causing them to take damage and be inflicted with confusion. | |
Creatine Powder | Helps build muscle + Speed up! | 1.25x Damage multiplier and + 0.3 Speed Up. | |
Credit of Trust |
|
Allows you to take one free item or consumable per shop. If you take more than one thing, the shop pedestals will despawn, Credit of Trust will be consumed, and 2 Greed minibosses will spawn. | |
Divine Vengeance | Revenge from above | Spawns several Holy Light beams upon taking damage. | |
D-Pad | You're in control | Gives various tear effects depending on which way you shoot and/or move your body. Includes effects like Homing, Mysterious Liquid, Spectral, Piercing, and more! | |
Experience Bar | Level Up! | Killing enemies causes Isaac to gain XP. Gaining enough XP causes Isaac to level up, increasing his stats slightly per level. | |
Fever | I don't feel so good | Tears down, Damage down, Shot speed up. Gives Isaac a shotgun-style burst of tears with strong knockback. These tears can poison, leave creep, or be booger tears. | |
Fly Boy | Chronenberged! | Progressively turns Isaac into a fly over the course of many floors, granting various forms of stat ups and other effects. After 6 floors the transformation is complete, and the "Beelzebub" transformation is granted. | |
Giant Boulder | Not be be confused with Small Rock | Flat +3 damage up. | |
Lil Greed | It corrupts your essence... | Grants a familiar that shoots three tears that have a chance to drop coins upon hitting an enemy. With the Greed Transformation, shoots 4 tears like Super Greed. Additionally respawns you as the Keeper if you die, consuming the familiar. | |
Guppy's Soul | At last, reunited | Gives a Guppy's Soul orbital that turns enemy shots into blue flies. | |
Harlequinitis | Bleeding tears | Gives Isaac a chance to fire a large, slow-moving blood tear that leaves a thick trail of red creep wherever it goes. This tear also deals extra damage. | |
Honeycomb | Fight or Flight | Honey creep no longer slows you down. Upon taking damage, you spawn 5-10 bees. | |
ISAAC is SAD | ITEM is REFERENCE. EFFECT is RANDOM. | Displays an "X is Y" statement when entering an uncleared room. These statements can effect anything in the room, for example "ENEMY is SLOW" will slow all enemies, or "PICKUP is YOU" will cause all pickups to follow Isaac's movements. | |
Jack o' Lantern | Spooky! | Bombs now cause fear on all enemies upon exploding, and shoot 4 fires in a + pattern. | |
Jar of Honey | Sweet tears | Tear Size up. 0.8x Shot Speed. Tears now inflict slowing and spawn puddles of honey creep on impact, similar to Mysterious Liquid. | |
Jetpack | Fwoosh! | Gives Isaac flight, and leaves a short fire trail. | |
Lil Devil | Fiery friend | Grants a familiar that shoots red fires periodically. These fires can destroy enemy projectiles and Shopkeepers. | |
Lil Dople | yddub rorriM | Grants an Abel-like familiar that does not shoot, but rather deals contact damage. | |
Lil Larry | Growing buddy | Grants a familiar that has multiple segments and chases around enemies. Each time you progress to a new floor, it gains another segment and increases damage. | |
Lil Scanner | Study thy enemy! | Grants a familiar that follows a target (can be controlled by shooting like Blue Baby's Only Friend) but also snaps onto nearby enemies to scan them. After hovering over an enemy for 3 consecutive seconds, it permanently makes that enemy take 1.5x more damage. | |
Medical Bill | The price for life | Removes all of Isaacs coins and gives him full HP. | |
Menstruation | I hate these days... | Red Poop no longer damages you. Whenever you take damage, you spawn red creep and some red poop. | |
Misery | Fate's definitely against you | Increases Tear rate based off of how many Broken Hearts Isaac has, and as well as adds three broken hearts. | |
Nocturia | My bladder hurts... | Shooting for 5 consecutive seconds makes you spawn a puddle of yellow creep when you stop firing. | |
Pet Rock Fly | Heavy buddy! | Gives Isaac a rock fly familiar, which will block shots, and slowly fly towards enemies and deal damage. | |
Pinball | Streak Bonus! | Gives Isaac the chance to shoot a high velocity, bouncy tear that increases in velocity and damage the more it bounces. | |
Plumber's Cap | It's-a-me! | Collecting 100 coins will reset the coin counter and give Isaac an extra life. | |
Poliomyelitis | Contagious handicapping | x0.8 speed multiplier. Upon touching an enemy, you have a chance of permanently slowing it down. They can then spread this effect by touching other enemies. | |
Prismatic Aberration | Im-prism-ment | Isaac has a chance to shoot prismatic tears, which will make enemies refract any tears that hit them into four more tears, similar to Angelic Prism. If an Imprismed enemy dies, it will also shoot a ring of 8 flashing black and white tears. | |
Revenge! | Mutually assured destruction | Whenever you take damage, all enemies in the room take damage proportionally to how much health you have left. (So taking a half heart of damage when you had 1 and a half hearts means all enemies take 1/3 of their max HP in damage) | |
Robo-Baby X | State-of-the-art | Gives Isaac a robo-baby familiar that will charge up as the player shoots. When fully charged, It will shoot a small Tech X ring, | |
Rotten Apple | Keeps the doctor... - actually, not really | -1 red heart, all stats up, and will refill 3 red hearts. | |
Rotten Eggs | Best leave this one to Ashens... | Fires an Ipecac tear upon taking damage. This tear cannot hurt Isaac. | |
Scented Candle | An enchanting smell! | Bounces around the room, inflicting a status effect to enemies in its aura. Status effect inflicted changes each room. | |
Schrödinger Tears | Quantum tears! | Gives Isaac a pseudo Triple-Shot with a wiggling effect. When one tear in the volley hits an enemy, the remaining two tears will vanish. | |
Eternal Seal | Faith up! | +1 Faith, +0.25 Damage, Chance for soul/golden hearts to drop when enemies die. | |
Seven-leaf Clover | Lucky! | + 7.77 Luck. | |
Gluttony's Soul | Feast in thy enemies! | Gives a Lil Gluttony orbital that blocks shots. After every 5 shots blocked, it fires a brimstone towards the last shot that hit it. | |
Speedrun | Go! | Adds a timer on the top of the screen upon entering a hostile room. If the room is cleared before the end of the timer, the room drops spawned are doubled. (This even works for Boss Rooms!) | |
Spinning Wheel | Round and round | Tears Up. After a short period of firing, each tear fired now comes out of Isaac 9° clockwise to the previous, resulting in a rotating spiral pattern. | |
Starvation | H...u...n...g...r...y... | Reduces your heart containers by 2 and adds 2 empty bone hearts. Your damage and tears scale with how many red heart containers you have, less containers resulting in higher fire rate but less damage. Speed and range also change according to your heart containers, increasing when you have a balanced amount of containers and bone hearts. | |
Strawberry Milk | Self-charging Shots! | Gives Isaac double damage and high fire rate. As Isaac fires, his damage will decrease. It will then replenish itself when he is not firing. | |
Tear Game | One for each of them | Gives Isaac a random tear effect that changes every time he kills an enemy, | |
Tech 3.14159265... | Irrational Technology | A technology laser will fire from Isaac's body in the direction he is walking. | |
Tech L | Pew! Pew! | Gives Isaac a massive shot speed up, and laser bolt tears that pierce and burn enemies. | |
Tonsil Stone | Straight out of your throat! | Tears have a chance to be tonsil stones, which have a poisonous aura, and can attach to enemies. Tonsil stones persist until the room is cleared. | |
Bloody Card | A bless or a curse? | Upon taking damage, there's a small chance your currently-held card will be activated. | |
Whipped Cream | Momentum! | Shot Speed multiplier. The faster your tears move, the more damage they deal. |
Hidden Items[ | ]
Due to certain items getting reworked, revamped, or being too buggy for the current version, several items have the "hidden" tag, preventing them from spawning in normal gameplay.
Active Items[ | ]
Name | Icon | Charges | Quote | Description |
---|---|---|---|---|
Assassin Instincts | 1 Room | From the shadows! | On use, fires a "dagger" projectile. Enemies hit by it take 1.5x damage, are inflicted with the bleeding effect and leave red creep (that damages you), until their death. | |
Banana Peel | 1 Room | Slip and slide! | Places a banana peel at Isaac's feet. Enemies will trip and slide on them, causing damage and confusion | |
Book Of Plagues | 4 rooms | Complete edition | Cycles through a series of plagues with each use, each effecting the room, the enemies in it, and/or the player in a variety of ways. | |
Champion Medal | 4 room | Everyone can be one | Turns all enemies in the room into champions, if possible. | |
Dad's Cigarette | Single-use | May contain carcinogens | Upon use, replaces 1 red heart container with a black heart and becomes a passive item that increases your damage. | |
Tear Soaker | Unlimited | Others may feel your sadness. Physically. | On use, a controllable red cursor appears on the floor. After a few seconds, Isaac will shoot a super high velocity and damage tear in that direction. |
Passive Collectables[ | ]
Name | Icon | Quote | Description |
---|---|---|---|
Blue Bombs | A blank slate | +5 Bombs. Bombs destroy all projectiles when they explode, and knockback all enemies. | |
Broccoli! | Come on! It's good for you! | All stats up. After firing a certain amount of shots (around 20 at base tears), you "vomit" the broccoli and lose the stats up. Resets every room. | |
Edith's Effigy | Gaze into the forbidden | Taking damage has a 20% chance of teleporting you into the enemy that hit you, dealing massive damage to them, and briefly confusing nearby enemies. Change to teleport increases with Faith. | |
Golden Champion Belt | No time for losers | Double damage dealt and recieved. Double champion spawn rate. Reduced champion pick-up drop rate to 10% | |
Pops! | Inflated friend | Floats around the room, blocking tears and projectiles that hit it. After taking enough shots, it will pop, dealing damage to and stunning all enemies. | |
Rubber Baby | Bouncy friend! | Grants a familiar that blocks enemy projectiles and shoots bouncy tears. | |
The Bliss | Just relaaaaax... | Speed down. The slower you are, the more damage you deal. | |
Yin and Yang | Balance is key | All stats up. Gives better stat ups the closer your Faith or Evil is to zero. |